Menu.gif
Midwest Research Institute logo and KC HQ photo Midwest Research Institute logo + solutions through science and technology Midwest Research Institute logo + solutions through science and technology Midwest Research Institute logo + solutions through science and technology
Home About MRI Research Services Working with MRI Outreach Careers

Nutraceutical and Natural Product Research

Nutraceutical and natural product research is diverse, challenging, and essential. As botanical preparations continue their growth and acceptance, questions concerning agronomy, product development, product safety, clinical effectiveness, and the evaluation of label claims are being posed by business, industry, and government.

MRI offers full-service laboratories:

Agricultural Research
and Production

  • Seed Treatment and Coating
  • Phytochemical Research
  • Raw Materials Selection

Botanical and Chemical Characterization

  • Methods Development and Validation
  • Chemical Properties Testing
  • LC/MS, GC/MS, NMR, IC, HPTLC, FTIR, GPC, MALDI-TOF/MS

Product and Process Development

  • Formulations
  • Nutrient Potency
  • Stability Testing
  • Quality Control Assays
  • Formulation Development and Testing (dissolution/disintegration)

New Applications and Markets

  • Microencapsulation
  • Microbiology/Molecular Biology
  • Proteomics
 

Contact:

Roger K. Harris,
Director, Product Sciences
(816) 753-7600,
ext. 1548

Dean Gray, Ph.D.
Senior Scientist
(816) 753-7600,
ext. 1325

 
     

Clinical Trials

  • Human and Animal
  • Toxicology

Activities in the field of natural product research include:

  • Clinical trials for popular botanical preparations are being conducted for industrial clients interested in proving the efficacy of their products.
  • We employ diverse analytical methods to evaluate label claims.
  • Work at MRI is performed to conform to EPA, GLP, and FDA cGMP, cGCP, and GLP regulations.
  • MRI utilizes a proprietary microencapsulation technology. Microencapsulation packages small bundles of a gas, liquid, or solid active ingredient within a second material that shields it from the environment.
  • MRI has equipment that performs seed coating with precise, uniform materials (such as mineral nutrients or fungicides), and this technology is being applied to enhance germination of certain species.
  • Analytical research is conducted on several botanicals including goldenseal (Hydrastis canadensis), kava kava (Piper methysticum), Ginkgo (Ginkgo biloba), black walnut (Juglans nigra), pine bark, and grape seed extract.
  • MRI conducts extraction, chemical
    characterization, analytical methods development, stability of marker compounds, and dose formulations for toxicology research.
  • Alternative analytical techniques (such as quantitative high performance thin layer chromatography) are being evaluated to increase sample throughput and minimize waste.

MRI also provides:

  • Field research in agricultural botanical chemistry
  • A natural-product field laboratory
  • Studies on alternative uses for natural products
  • Research experience in stress physiology, phytochemistry, entomology, and mineral nutrition

Natural products MRI has studied include:

Aloe
Arnica
Astragalus
Bilberry
Black walnut
Calamus
Calendula
Colchicum
Comfrey
Echinacea
Flax
Ginkgo
Goldenseal
Grape seed
Green tea
Helonias
Kava kava
Lavender
Ma huang
Meadowsweet
Milk thistle
Motherwort
Mullein
Nettle seed
Oregon grape
Periwinkle
Pine bark
Plantain
Puncture vine
St. John's wort
Stone root
Suma
Tiger lily
Usnea
Valerian
Wild yam
Willow
Yohimbe

back to top

 

About MRI - Research Services - Working with MRI - Outreach - Careers - News - Search - Contact Us - Site Map
National Defense - Health Sciences - Agriculture & Food Safety - Engineering - National Renewable Energy Laboratory

Midwest Research Institute, 425 Volker Boulevard, Kansas City, Missouri 64110
(816) 753-7600

© Midwest Research Institute
All rights reserved.